A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells

Pancreatic endocrine cell differentiation is orchestrated by the action of transcription factors that operate in a gene regulatory network to activate endocrine lineage genes and repress lineage-inappropriate genes. MicroRNAs (miRNAs) are important modulators of gene expression, yet their role in en...

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Publicado en:iScience
Autores principales: Jin, Wen, Mulas, Francesca, Gaertner, Bjoern, Sui, Yinghui, Wang, Jinzhao, Matta, Ileana, Zeng, Chun, Vinckier, Nicholas, Wang, Allen, Nguyen-Ngoc, Kim-Vy, Chiou, Joshua, Kaestner, Klaus H., Frazer, Kelly A., Carrano, Andrea C., Shih, Hung-Ping, Sander, Maike
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889369/
https://ncbi.nlm.nih.gov/pubmed/31733514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.10.063
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