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Eribulin rapidly inhibits TGF-β-induced Snail expression and can induce Slug expression in a Smad4-dependent manner

BACKGROUND: Evidence shows that the anticancer effects of microtubule targeting agents are not due solely to their antimitotic activities but also their ability to impair microtubule-dependent oncogenic signalling. METHODS: The effects of microtubule targeting agents on regulators of TGF-β-induced e...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Kaul, Roma, Risinger, April L., Mooberry, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889360/
https://ncbi.nlm.nih.gov/pubmed/31481735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0556-9
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