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Oncometabolite modification of Keap1 links GSTZ1 deficiency with cancer
Metabolic abnormalities are emerging as an active driver to the development, progression and metastasis of various tumors. In the recent issue of the EMBO Journal, Yang and colleagues identified that succinylacetone (SA) could act as an oncometabolite and that accumulation of SA activates the NRF2/I...
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| Publicado no: | Genes Dis |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Chongqing Medical University
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6889240/ https://ncbi.nlm.nih.gov/pubmed/31832512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.10.005 |
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