Llwytho...

Oncometabolite modification of Keap1 links GSTZ1 deficiency with cancer

Metabolic abnormalities are emerging as an active driver to the development, progression and metastasis of various tumors. In the recent issue of the EMBO Journal, Yang and colleagues identified that succinylacetone (SA) could act as an oncometabolite and that accumulation of SA activates the NRF2/I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dis
Prif Awduron: Guo, Weijie, Zhou, Binhua P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Chongqing Medical University 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889240/
https://ncbi.nlm.nih.gov/pubmed/31832512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2019.10.005
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!