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The ArfGAP ASAP1 Controls Actin Stress Fiber Organization via Its N-BAR Domain

ASAP1 is a multi-domain ArfGAP that controls cell migration, spreading, and focal adhesion dynamics. Although its GAP activity contributes to remodeling of the actin cytoskeleton, it does not fully explain all cellular functions of ASAP1. Here we find that ASAP1 regulates actin filament assembly dir...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Gasilina, Anjelika, Vitali, Teresa, Luo, Ruibai, Jian, Xiaoying, Randazzo, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889188/
https://ncbi.nlm.nih.gov/pubmed/31785555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.11.015
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