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Autoinhibition of Arf GTPase-activating Protein Activity by the BAR Domain in ASAP1
ASAP1 is an Arf GTPase-activating protein (GAP) that functions on membrane surfaces to catalyze the hydrolysis of GTP bound to Arf. ASAP1 contains a tandem of BAR, pleckstrin homology (PH), and Arf GAP domains and contributes to the formation of invadopodia and podosomes. The PH domain interacts wit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615509/ https://ncbi.nlm.nih.gov/pubmed/19017632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804218200 |
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