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Autoinhibition of Arf GTPase-activating Protein Activity by the BAR Domain in ASAP1

ASAP1 is an Arf GTPase-activating protein (GAP) that functions on membrane surfaces to catalyze the hydrolysis of GTP bound to Arf. ASAP1 contains a tandem of BAR, pleckstrin homology (PH), and Arf GAP domains and contributes to the formation of invadopodia and podosomes. The PH domain interacts wit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jian, Xiaoying, Brown, Patrick, Schuck, Peter, Gruschus, James M., Balbo, Andrea, Hinshaw, Jenny E., Randazzo, Paul A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615509/
https://ncbi.nlm.nih.gov/pubmed/19017632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804218200
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