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Synthesis and biological activities of two camptothecin derivatives against Spodoptera exigua

Camptothecin (CPT), a natural alkaloid isolated from Camptotheca acuminata Decne, is found to show potential insecticidal activities with unique action mechanisms by targeting at DNA-topoisomease I (Top1) complex and inducing cell apoptosis. To improve the efficacy against insect pests, two camptoth...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Yang, Fulai, Wang, Liping, Zhang, Lan, Zhang, Yanning, Mao, Liangang, Jiang, Hongyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889156/
https://ncbi.nlm.nih.gov/pubmed/31792297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54596-y
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