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Sulphide as a leaving group: highly stereoselective bromination of alkyl phenyl sulphides

A conceptionally novel nucleophilic substitution approach to synthetically important alkyl bromides is presented. Using molecular bromine (Br(2)), readily available secondary benzyl and tertiary alkyl phenyl sulphides are converted into the corresponding bromides under exceptionally mild, acid- and...

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Vydáno v:Chem Sci
Hlavní autoři: Canestrari, Daniele, Cioffi, Caterina, Biancofiore, Ilaria, Lancianesi, Stefano, Ghisu, Lorenza, Ruether, Manuel, O'Brien, John, Adamo, Mauro F. A., Ibrahim, Hasim
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889150/
https://ncbi.nlm.nih.gov/pubmed/31827746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc03560e
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