DPP8 is a novel therapeutic target for multiple myeloma

Dipeptidyl peptidases (DPPs) are proteolytic enzymes that are ideal therapeutic targets in human diseases. Indeed, DPP4 inhibitors are widely used in clinical practice as anti-diabetic agents. In this paper, we show that DPP4 inhibitors also induced cell death in multiple human myeloma cells. Among...

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Publicat a:Sci Rep
Autors principals: Sato, Tsutomu, Tatekoshi, Ayumi, Takada, Kohichi, Iyama, Satoshi, Kamihara, Yusuke, Jawaid, Paras, Rehman, Mati Ur, Noguchi, Kyo, Kondo, Takashi, Kajikawa, Sayaka, Arita, Kotaro, Wada, Akinori, Murakami, Jun, Arai, Miho, Yasuda, Ichiro, Dang, Nam H., Hatano, Ryo, Iwao, Noriaki, Ohnuma, Kei, Morimoto, Chikao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889119/
https://ncbi.nlm.nih.gov/pubmed/31792328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54695-w
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