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Downregulation of nuclear progestin receptor (Pgr) and subfertility in double knockouts of progestin receptor membrane component 1 (pgrmc1) and pgrmc2 in zebrafish

The progestin receptor membrane components (Pgrmcs) contain two paralogs, Pgrmc1 and Pgrmc2. Our previous research into single knockout of Pgrmc1 or Pgrmc2 suggests that Pgrmc1 and Pgrmc2 regulate membrane progestin receptor or steroid synthesis and therefore female fertility in zebrafish. Additiona...

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Publicado en:Gen Comp Endocrinol
Autores principales: Wu, Xin-Jun, Zhu, Yong
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888933/
https://ncbi.nlm.nih.gov/pubmed/31536721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygcen.2019.113275
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