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Downregulation of nuclear progestin receptor (Pgr) and subfertility in double knockouts of progestin receptor membrane component 1 (pgrmc1) and pgrmc2 in zebrafish

The progestin receptor membrane components (Pgrmcs) contain two paralogs, Pgrmc1 and Pgrmc2. Our previous research into single knockout of Pgrmc1 or Pgrmc2 suggests that Pgrmc1 and Pgrmc2 regulate membrane progestin receptor or steroid synthesis and therefore female fertility in zebrafish. Additiona...

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Detalhes bibliográficos
Publicado no:Gen Comp Endocrinol
Main Authors: Wu, Xin-Jun, Zhu, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888933/
https://ncbi.nlm.nih.gov/pubmed/31536721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygcen.2019.113275
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