The phosphodiesterase 10 inhibitor papaverine exerts anti-inflammatory and neuroprotective effects via the PKA signaling pathway in neuroinflammation and Parkinson’s disease mouse models

BACKGROUND: Neuroinflammation plays a pivotal role in the pathogenesis of Parkinson’s disease (PD). Thus, the development of agents that can control neuroinflammation has been suggested as a promising therapeutic strategy for PD. In the present study, we investigated whether the phosphodiesterase (P...

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Dettagli Bibliografici
Pubblicato in:J Neuroinflammation
Autori principali: Lee, Yu-Young, Park, Jin-Sun, Leem, Yea-Hyun, Park, Jung-Eun, Kim, Do-Yeon, Choi, Youn-Hee, Park, Eun-Mi, Kang, Jihee Lee, Kim, Hee-Sun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888927/
https://ncbi.nlm.nih.gov/pubmed/31791357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1649-3
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