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A novel gemcitabine derivative-loaded liposome with great pancreas-targeting ability
Gemcitabine (Gem) is a standard first-line treatment for pancreatic cancer (PC). However, its chemotherapeutic efficacy is hampered by various limitations such as short half-life, metabolic inactivation, and lack of tumor localizing. We previously synthesized a lipophilic Gem derivative (Gem formyl...
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| Publicado no: | Acta Pharmacol Sin |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6888841/ https://ncbi.nlm.nih.gov/pubmed/31015736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0227-7 |
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