YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways

BACKGROUND: Pancreatic cancer (PDAC) is a highly invasive cancer with poor prognosis. Recent research has found that the transcription factor Yin Yang 1 (YY1) plays an inhibitory role in the development of pancreatic cancer. It has been reported that tubulin polymerisation-promoting protein (TPPP) p...

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Publicado no:Br J Cancer
Main Authors: Chen, Qun, Yang, Chuang, Chen, Lei, Zhang, Jing-Jing, Ge, Wan-Li, Yuan, Hao, Meng, Ling-Dong, Huang, Xu-Min, Shen, Peng, Miao, Yi, Jiang, Kui-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6888832/
https://ncbi.nlm.nih.gov/pubmed/31631174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0604-5
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