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Knockdown of Pyruvate Kinase M2 Inhibits Cell Proliferation, Metabolism, and Migration in Renal Cell Carcinoma

Emerging evidence indicates that the activity of pyruvate kinase M2 (PKM2) isoform is crucial for the survival of tumor cells. However, the molecular mechanism underlying the function of PKM2 in renal cancer is undetermined. Here, we reveal the overexpression of PKM2 in the proximal tubule of renal...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Dey, Prasanta, Son, Ji Yeon, Kundu, Amit, Kim, Kyeong Seok, Lee, Yura, Yoon, Kyungsil, Yoon, Sungpil, Lee, Byung Mu, Nam, Ki Taek, Kim, Hyung Sik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887957/
https://ncbi.nlm.nih.gov/pubmed/31717694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20225622
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