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Designing Clinical Trials in Pediatric Nonalcoholic Steatohepatitis: Tips for Patient Selection and Appropriate Endpoints

Nonalcoholic fatty liver disease (NAFLD) is common in children and may progress to nonalcoholic steatohepatitis (NASH), advanced fibrosis, and even cirrhosis in childhood or early adulthood, indicating the need for pharmacologic treatment in this age group. Multiple trials are evaluating different t...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Alkhouri, Naim, Kohli, Rohit, Feldstein, Ariel E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887671/
https://ncbi.nlm.nih.gov/pubmed/31832567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1449
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