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Designing Clinical Trials in Pediatric Nonalcoholic Steatohepatitis: Tips for Patient Selection and Appropriate Endpoints

Nonalcoholic fatty liver disease (NAFLD) is common in children and may progress to nonalcoholic steatohepatitis (NASH), advanced fibrosis, and even cirrhosis in childhood or early adulthood, indicating the need for pharmacologic treatment in this age group. Multiple trials are evaluating different t...

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Bibliografiske detaljer
Udgivet i:Hepatol Commun
Main Authors: Alkhouri, Naim, Kohli, Rohit, Feldstein, Ariel E.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887671/
https://ncbi.nlm.nih.gov/pubmed/31832567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1449
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