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Three‐dimensional electron microscopy techniques for unravelling mitochondrial dysfunction in heart failure and identification of new pharmacological targets

A hallmark of heart failure is mitochondrial dysfunction leading to a bioenergetics imbalance in the myocardium. Consequently, there is much interest in targeting mitochondrial abnormalities to attenuate the pathogenesis of heart failure. This review discusses (i) how electron microscopy (EM) techni...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Daghistani, Hussam M, Rajab, Bodour S, Kitmitto, Ashraf
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887664/
https://ncbi.nlm.nih.gov/pubmed/30225980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14499
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