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MiR‐195 and miR‐497 suppress tumorigenesis in lung cancer by inhibiting SMURF2‐induced TGF‐β receptor I ubiquitination

SMURF2 is a member of the HECT family of E3 ubiquitin ligases that have important roles as a negative regulator of transforming growth factor‐β (TGF‐β) signaling through ubiquitin‐mediated degradation of TGF‐β receptor I. However, the regulatory mechanism of SMURF2 is largely unknown. In this study,...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Oncol
Κύριοι συγγραφείς: Chae, Dong‐Kyu, Park, Jinyoung, Cho, Moonsoo, Ban, Eunmi, Jang, Mihue, Yoo, Young Sook, Kim, Eunice EunKyeong, Baik, Ja‐Hyun, Song, Eun Joo
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887584/
https://ncbi.nlm.nih.gov/pubmed/31581360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12581
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