Physical PEGylation Enhances The Cytotoxicity Of 5-Fluorouracil-Loaded PLGA And PCL Nanoparticles

PURPOSE: The main goal of this study is to evaluate the impact of physical incorporation of polyethylene glycol (PEG) into 5-fluorouracil (5-FU)-loaded polymeric nanoparticles (NPs). METHODS: The 5-FU-loaded NPs were prepared utilizing a simple double emulsion method using polycaprolactone (PCL) and...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Ashour, Abdelkader E, Badran, Mohammad, Kumar, Ashok, Hussain, Tajamul, Alsarra, Ibrahim A, Yassin, Alaa Eldeen B
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886887/
https://ncbi.nlm.nih.gov/pubmed/31819428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S223368
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