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Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase

Dengue is a mosquito-borne viral infection that has spread globally in recent years. Around half of the world’s population, especially in the tropics and subtropics, is at risk of infection. Every year, 50–100 million clinical cases are reported, and more than 500,000 patients develop the symptoms o...

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Podrobná bibliografie
Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Shimizu, Hideaki, Saito, Akatsuki, Mikuni, Junko, Nakayama, Emi E., Koyama, Hiroo, Honma, Teruki, Shirouzu, Mikako, Sekine, Shun-ichi, Shioda, Tatsuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886872/
https://ncbi.nlm.nih.gov/pubmed/31738758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007894
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