Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase

Dengue is a mosquito-borne viral infection that has spread globally in recent years. Around half of the world’s population, especially in the tropics and subtropics, is at risk of infection. Every year, 50–100 million clinical cases are reported, and more than 500,000 patients develop the symptoms o...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Principais autores: Shimizu, Hideaki, Saito, Akatsuki, Mikuni, Junko, Nakayama, Emi E., Koyama, Hiroo, Honma, Teruki, Shirouzu, Mikako, Sekine, Shun-ichi, Shioda, Tatsuo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886872/
https://ncbi.nlm.nih.gov/pubmed/31738758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007894
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