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CRL4 regulates recombination and synaptonemal complex aggregation in the Caenorhabditis elegans germline

To maintain the integrity of the genome, meiotic DNA double strand breaks (DSBs) need to form by the meiosis-specific nuclease Spo11 and be repaired by homologous recombination. One class of products formed by recombination are crossovers, which are required for proper chromosome segregation in the...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Alleva, Benjamin, Clausen, Sean, Koury, Emily, Hefel, Adam, Smolikove, Sarit
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886871/
https://ncbi.nlm.nih.gov/pubmed/31738749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008486
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