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CRL4 regulates recombination and synaptonemal complex aggregation in the Caenorhabditis elegans germline

To maintain the integrity of the genome, meiotic DNA double strand breaks (DSBs) need to form by the meiosis-specific nuclease Spo11 and be repaired by homologous recombination. One class of products formed by recombination are crossovers, which are required for proper chromosome segregation in the...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Alleva, Benjamin, Clausen, Sean, Koury, Emily, Hefel, Adam, Smolikove, Sarit
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886871/
https://ncbi.nlm.nih.gov/pubmed/31738749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008486
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