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Robust blind spectral unmixing for fluorescence microscopy using unsupervised learning

Due to the overlapping emission spectra of fluorophores, fluorescence microscopy images often have bleed-through problems, leading to a false positive detection. This problem is almost unavoidable when the samples are labeled with three or more fluorophores, and the situation is complicated even fur...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: McRae, Tristan D., Oleksyn, David, Miller, Jim, Gao, Yu-Rong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886781/
https://ncbi.nlm.nih.gov/pubmed/31790435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0225410
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