The use of BRAF V600E mutation-specific immunohistochemistry in pediatric Langerhans cell histiocytosis

BRAF p.V600E mutations are detected in greater than 50% of pediatric Langerhans cell histiocytosis (LCH) lesions. However, the use of mutation-specific BRAF V600E immunohistochemistry (IHC) as a surrogate for molecular testing in pediatric LCH is unknown. We tested the mutation-specific BRAF V600E m...

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Detalhes bibliográficos
Publicado no:Hematol Oncol
Main Authors: Ballester, Leomar Y., Cantu, Miguel D., Lim, Karen P.H., Sarabia, Stephen F., Ferguson, Lizmery Suarez, Webb, C. Renee, Allen, Carl E., McClain, Kenneth L., Mohila, Carrie A., Punia, Jyotinder N., Roy, Angshumoy, López-Terrada, Dolores H., Hicks, M. John, Fisher, Kevin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886693/
https://ncbi.nlm.nih.gov/pubmed/28219109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hon.2388
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