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Loop-to-helix transition in the structure of multidrug regulator AcrR at the entrance of the drug-binding cavity

Multidrug transcription regulator AcrR from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 belongs to the tetracycline repressor family, one of the largest groups of bacterial transcription factors. The crystal structure of dimeric AcrR was determined and refined to 1.56 Å resoluti...

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Detalhes bibliográficos
Publicado no:J Struct Biol
Main Authors: Manjasetty, Babu A., Halavaty, Andrei S., Luan, Chi-Hao, Osipiuk, Jerzy, Mulligan, Rory, Kwon, Keehwan, Anderson, Wayne F., Joachimiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886526/
https://ncbi.nlm.nih.gov/pubmed/26796657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2016.01.008
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