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Joint between-sample normalization and differential expression detection through ℓ(0)-regularized regression
BACKGROUND: A fundamental problem in RNA-seq data analysis is to identify genes or exons that are differentially expressed with varying experimental conditions based on the read counts. The relativeness of RNA-seq measurements makes the between-sample normalization of read counts an essential step i...
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| Wydane w: | BMC Bioinformatics |
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| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6886201/ https://ncbi.nlm.nih.gov/pubmed/31787074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-3070-4 |
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