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COSMOS: accurate detection of somatic structural variations through asymmetric comparison between tumor and normal samples

An important challenge in cancer genomics is precise detection of structural variations (SVs) by high-throughput short-read sequencing, which is hampered by the high false discovery rates of existing analysis tools. Here, we propose an accurate SV detection method named COSMOS, which compares the st...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Yamagata, Koichi, Yamanishi, Ayako, Kokubu, Chikara, Takeda, Junji, Sese, Jun
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856976/
https://ncbi.nlm.nih.gov/pubmed/26833260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw026
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