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Uncovering Thousands of New Peptides with Sequence-Mask-Search Hybrid De Novo Peptide Sequencing Framework

Typical analyses of mass spectrometry data only identify amino acid sequences that exist in reference databases. This restricts the possibility of discovering new peptides such as those that contain uncharacterized mutations or originate from unexpected processing of RNAs and proteins. De novo pepti...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Karunratanakul, Korrawe, Tang, Hsin-Yao, Speicher, David W., Chuangsuwanich, Ekapol, Sriswasdi, Sira
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885704/
https://ncbi.nlm.nih.gov/pubmed/31591261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR119.001656
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