No evidence of Gremlin1-mediated activation of VEGFR2 signaling in endothelial cells

Canonical Gremlin1 (GREM1) signaling involves binding to and sequestering bone morphogenetic proteins (BMPs) in the extracellular matrix, preventing the activation of cognate BMP receptor. Exquisite temporospatial control of the GREM1-BMP interaction is required during development, and perturbation...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Dutton, Louise R., O'Neill, Christina L., Medina, Reinhold J., Brazil, Derek P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accelerated Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885617/
https://ncbi.nlm.nih.gov/pubmed/31604823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.010148
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