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No evidence of Gremlin1-mediated activation of VEGFR2 signaling in endothelial cells

Canonical Gremlin1 (GREM1) signaling involves binding to and sequestering bone morphogenetic proteins (BMPs) in the extracellular matrix, preventing the activation of cognate BMP receptor. Exquisite temporospatial control of the GREM1-BMP interaction is required during development, and perturbation...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Dutton, Louise R., O'Neill, Christina L., Medina, Reinhold J., Brazil, Derek P.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885617/
https://ncbi.nlm.nih.gov/pubmed/31604823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.010148
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