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A novel oncolytic adenovirus inhibits hepatocellular carcinoma growth

Objective: To evaluate the inhibitory role of a novel oncolytic adenovirus (OA), GP73-SphK1sR-Ad5, on the growth of hepatocellular carcinoma (HCC). Methods: GP73-SphK1sR-Ad5 was constructed by integrating Golgi protein 73 (GP73) promoter and sphingosine kinase 1 (SphK1)-short hairpin RNA (shRNA) int...

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Detalhes bibliográficos
Publicado no:J Zhejiang Univ Sci B
Main Authors: Bai, Yu-huan, Yun, Xiao-jing, Xue, Yan, Zhou, Ting, Sun, Xin, Gao, Yan-jing
Formato: Artigo
Idioma:Inglês
Publicado em: Zhejiang University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885404/
https://ncbi.nlm.nih.gov/pubmed/31749347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1900089
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