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Centella asiatica (Gotu kola) ethanol extract up-regulates hippocampal brain-derived neurotrophic factor (BDNF), tyrosine kinase B (TrkB) and extracellular signal-regulated protein kinase 1/2 (ERK1/2) signaling in chronic electrical stress model in rats

OBJECTIVE(S): Impairment of hippocampus function as a center for memory processing occurs due to stress. Centella asiatica L. (Gotu kola) is known to improve memory, intelligence, and neural protection although the precise mechanism is not well understood. This study aimed to investigate the effects...

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Bibliographic Details
Published in:Iran J Basic Med Sci
Main Authors: Sari, Dwi Cahyani Ratna, Arfian, Nur, Tranggono, Untung, Setyaningsih, Wiwit Ananda Wahyu, Romi, Muhammad Mansyur, Emoto, Noriaki
Format: Artigo
Language:Inglês
Published: Mashhad University of Medical Sciences 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885393/
https://ncbi.nlm.nih.gov/pubmed/31998466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/ijbms.2019.29012.7002
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