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Uric acid causes kidney injury through inducing fibroblast expansion, Endothelin-1 expression, and inflammation
BACKGROUND: Uric acid (UA) plays important roles in inducing renal inflammation, intra-renal vasoconstriction and renal damage. Endothelin-1 (ET-1) is a well-known profibrotic factor in the kidney and is associated with fibroblast expansion. We examined the role of hyperuricemia conditions in causin...
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| Publicado no: | BMC Nephrol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5664905/ https://ncbi.nlm.nih.gov/pubmed/29089036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-017-0736-x |
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