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Carvedilol Inhibits Angiotensin II-Induced Proliferation and Contraction in Hepatic Stellate Cells through the RhoA/Rho-Kinase Pathway

AIM: Carvedilol is a nonselective beta-blocker used to reduce portal hypertension. This study investigated the effects and potential mechanisms of carvedilol in angiotensin II- (Ang II-) induced hepatic stellate cell (HSC) proliferation and contraction. METHODS: The effect of carvedilol on HSC proli...

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Dettagli Bibliografici
Pubblicato in:Biomed Res Int
Autori principali: Wu, Ying, Li, Zhen, Wang, Sining, Xiu, Aiyuan, Zhang, Chunqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885148/
https://ncbi.nlm.nih.gov/pubmed/31828132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7932046
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