Enrichment of persisters enabled by a ß-lactam-induced filamentation method reveals their stochastic single-cell awakening

When exposed to lethal doses of antibiotics, bacterial populations are most often not completely eradicated. A small number of phenotypic variants, defined as ‘persisters’, are refractory to antibiotics and survive treatment. Despite their involvement in relapsing infections, processes determining p...

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Udgivet i:Commun Biol
Main Authors: Windels, Etthel M., Ben Meriem, Zacchari, Zahir, Taiyeb, Verstrepen, Kevin J., Hersen, Pascal, Van den Bergh, Bram, Michiels, Jan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884588/
https://ncbi.nlm.nih.gov/pubmed/31815194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0672-3
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