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Response to Olaparib in a Patient with Germline BRCA2 Mutation and Breast Cancer Leptomeningeal Carcinomatosis

Leptomeningeal carcinomatosis (LC) is a devastating complication of metastatic cancer that disproportionately affects patients with advanced breast cancer. Moreover, those with BRCA1/2-mutated disease more often experience leptomeningeal metastasis. Treatment options for LC are limited and often inc...

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Publicat a:NPJ Breast Cancer
Autors principals: Exman, Pedro, Mallery, Robert M., Lin, Nancy U., Parsons, Heather A.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884546/
https://ncbi.nlm.nih.gov/pubmed/31815182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-019-0139-1
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