Olaparib is effective for recurrent urothelial carcinoma with BRCA2 pathogenic germline mutation: first report on olaparib response in recurrent UC

Urothelial carcinoma (UC) is a common malignancy of the lower and upper urinary tract. Recurrent UC has poor prognosis due to delayed diagnosis and a lack of clinical management guidance, especially for upper urinary tract UC. Patients with germline or somatic BRCA1/2 mutations are a special populat...

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Bibliographic Details
Published in:Ther Adv Med Oncol
Main Authors: Yang, Hong, Liu, Zhimin, Wang, Yufang, Li, Jun, Li, Ruiqian, Wang, Qilin, Hu, Chen, Jiang, Haiyang, Wu, Hongyi, Song, Lele, Bai, Yu
Format: Artigo
Language:Inglês
Published: SAGE Publications 2020
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7675892/
https://ncbi.nlm.nih.gov/pubmed/33240400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835920970845
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