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Altered generation of ciliated cells in chronic obstructive pulmonary disease

In COPD, epithelial changes are prominent features in the airways, such as goblet cell hyperplasia and squamous metaplasia. In contrast, it remains unclear whether ciliated cells are reduced and which pathways dysregulate epithelial differentiation. We hypothesized that bronchial epithelial cell lin...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Gohy, Sophie, Carlier, François M., Fregimilicka, Chantal, Detry, Bruno, Lecocq, Marylène, Ladjemi, Maha Zohra, Verleden, Stijn, Hoton, Delphine, Weynand, Birgit, Bouzin, Caroline, Pilette, Charles
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884487/
https://ncbi.nlm.nih.gov/pubmed/31784664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54292-x
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