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Altered generation of ciliated cells in chronic obstructive pulmonary disease

In COPD, epithelial changes are prominent features in the airways, such as goblet cell hyperplasia and squamous metaplasia. In contrast, it remains unclear whether ciliated cells are reduced and which pathways dysregulate epithelial differentiation. We hypothesized that bronchial epithelial cell lin...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Gohy, Sophie, Carlier, François M., Fregimilicka, Chantal, Detry, Bruno, Lecocq, Marylène, Ladjemi, Maha Zohra, Verleden, Stijn, Hoton, Delphine, Weynand, Birgit, Bouzin, Caroline, Pilette, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884487/
https://ncbi.nlm.nih.gov/pubmed/31784664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54292-x
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