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A SUMO-dependent pathway controls elongating RNA Polymerase II upon UV-induced damage

RNA polymerase II (RNAPII) is the workhorse of eukaryotic transcription and produces messenger RNAs and small nuclear RNAs. Stalling of RNAPII caused by transcription obstacles such as DNA damage threatens functional gene expression and is linked to transcription-coupled DNA repair. To restore trans...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Heckmann, Irina, Kern, Maximilian J., Pfander, Boris, Jentsch, Stefan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884465/
https://ncbi.nlm.nih.gov/pubmed/31784551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54027-y
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