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RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors

Oxidative lesions represent the most abundant DNA lesions within the cell. In the present study, we investigated the impact of the oxidative lesions 8-oxoguanine, thymine glycol and 5-hydroxyuracil on RNA polymerase II (RNA pol II) transcription using a well-defined in vitro transcription system. We...

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Bibliografiske detaljer
Main Authors: Charlet-Berguerand, Nicolas, Feuerhahn, Sascha, Kong, Stephanie E, Ziserman, Howard, Conaway, Joan W, Conaway, Ronald, Egly, Jean Marc
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679758/
https://ncbi.nlm.nih.gov/pubmed/17110932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601403
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