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RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors
Oxidative lesions represent the most abundant DNA lesions within the cell. In the present study, we investigated the impact of the oxidative lesions 8-oxoguanine, thymine glycol and 5-hydroxyuracil on RNA polymerase II (RNA pol II) transcription using a well-defined in vitro transcription system. We...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1679758/ https://ncbi.nlm.nih.gov/pubmed/17110932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601403 |
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