Kemp Eliminases of the AlleyCat Family Possess High Substrate Promiscuity

Minimalist enzymes designed to catalyze model reactions provide useful starting points for creating catalysts for practically important chemical transformations. We have shown that Kemp eliminases of the AlleyCat family facilitate conversion of leflunomide (an immunosupressor pro-drug) to its active...

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Bibliografiset tiedot
Julkaisussa:ChemCatChem
Päätekijät: Caselle, Elizabeth A., Yoon, Jennifer H., Bhattacharya, Sagar, Rempillo, Joel J.L., Lengyel, Zsófia, D’Souza, Areetha, Moroz, Yurii S., Tolbert, Patricia L., Volkov, Alexander N., Forconi, Marcello, Castañeda, Carlos A., Makhlynets, Olga V., Korendovych, Ivan V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884320/
https://ncbi.nlm.nih.gov/pubmed/31788134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cctc.201801994
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