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Too Much of a Good Thing: Detrimental Effects of Interferon

Healthy tissues of the body express relatively low basal levels of interferons. However, following detection of microbial invasion by sentinel receptors, a cascade of events initiates leading to the transcriptional induction of interferon genes. Interferons are secreted and act primarily as paracrin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Semin Immunol
1. Verfasser: Reich, Nancy C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884074/
https://ncbi.nlm.nih.gov/pubmed/31771763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2019.101282
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