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Too Much of a Good Thing: Detrimental Effects of Interferon
Healthy tissues of the body express relatively low basal levels of interferons. However, following detection of microbial invasion by sentinel receptors, a cascade of events initiates leading to the transcriptional induction of interferon genes. Interferons are secreted and act primarily as paracrin...
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| Published in: | Semin Immunol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6884074/ https://ncbi.nlm.nih.gov/pubmed/31771763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2019.101282 |
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