Distinct effects of orexin receptor antagonist and GABA(A) agonist on sleep and physical/cognitive functions after forced awakening

The majority of patients with insomnia are treated with hypnotic agents. In the present study, we evaluated the side-effect profile of an orexin receptor antagonist and γ-aminobutyric acid A (GABA(A)) receptor agonist on physical/cognitive functions upon forced awakening. This double-blind, randomiz...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Seol, Jaehoon, Fujii, Yuya, Park, Insung, Suzuki, Yoko, Kawana, Fusae, Yajima, Katsuhiko, Fukusumi, Shoji, Okura, Tomohiro, Satoh, Makoto, Tokuyama, Kumpei, Kokubo, Toshio, Yanagisawa, Masashi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883838/
https://ncbi.nlm.nih.gov/pubmed/31712421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907354116
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