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Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners
Histone variants fine-tune transcription, replication, DNA damage repair, and faithful chromosome segregation. Whether and how nucleosome variants encode unique mechanical properties to their cognate chromatin structures remains elusive. Here, using in silico and in vitro nanoindentation methods, ex...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6883791/ https://ncbi.nlm.nih.gov/pubmed/31712435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911880116 |
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