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The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke

BACKGROUND: Preserving the integrity of the blood-brain barrier (BBB) is beneficial to avoid further brain damage after acute ischemic stroke (AIS). Astrocytes, an important component of the BBB, promote BBB breakdown in subjects with AIS by secreting inflammatory factors. The glucagon-like peptide-...

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Podrobná bibliografie
Vydáno v:J Neuroinflammation
Hlavní autoři: Shan, Yilong, Tan, Sha, Lin, Yinyao, Liao, Siyuan, Zhang, Bingjun, Chen, Xiaodong, Wang, Jihui, Deng, Zhezhi, Zeng, Qin, Zhang, Lei, Wang, Yuge, Hu, Xueqiang, Qiu, Wei, Peng, Lisheng, Lu, Zhengqi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883580/
https://ncbi.nlm.nih.gov/pubmed/31779652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1638-6
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