The glucagon-like peptide-1 receptor agonist reduces inflammation and blood-brain barrier breakdown in an astrocyte-dependent manner in experimental stroke

BACKGROUND: Preserving the integrity of the blood-brain barrier (BBB) is beneficial to avoid further brain damage after acute ischemic stroke (AIS). Astrocytes, an important component of the BBB, promote BBB breakdown in subjects with AIS by secreting inflammatory factors. The glucagon-like peptide-...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Shan, Yilong, Tan, Sha, Lin, Yinyao, Liao, Siyuan, Zhang, Bingjun, Chen, Xiaodong, Wang, Jihui, Deng, Zhezhi, Zeng, Qin, Zhang, Lei, Wang, Yuge, Hu, Xueqiang, Qiu, Wei, Peng, Lisheng, Lu, Zhengqi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883580/
https://ncbi.nlm.nih.gov/pubmed/31779652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1638-6
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