TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection

TGFβ is an anti-inflammatory molecule that suppresses pro-inflammatory immune responses. Previously, we demonstrated that chronic filarial infection has a beneficial impact on Escherichia coli-induced sepsis. In the present study, we investigated whether this protective effect is dependent on TGFβ s...

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I publikationen:GMS Infect Dis
Huvudupphovsmän: Buerfent, Benedikt C., Ajendra, Jesuthas, Stamminger, Wiebke, Gondorf, Fabian, Hoerauf, Achim, Hübner, Marc P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: German Medical Science GMS Publishing House 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6883344/
https://ncbi.nlm.nih.gov/pubmed/31815088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3205/id000044
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